Acetaminophen or Ibuprofen – For Fever and Body Aches

Fever, sore throat, and muscle aches are common symptoms of both colds and the flu. Acetaminophen (like Tylenol) or ibuprofen (like Advil or Motrin) are essential over-the-counter (OTC) medications for managing discomfort and lowering fever. These medications are safe for most adults when used as directed and are widely available in both regular strength and children’s formulas.

Pharmacist Tip: Keep both on hand if possible — ibuprofen is anti-inflammatory, while acetaminophen is often gentler on the stomach. Make sure to read the label carefully and never double-dose, especially with combination products.

Decongestants for Sinus Pressure Relief

A blocked nose can be one of the most frustrating symptoms of a cold or flu. Decongestants help reduce the swelling in your nasal passages, allowing for better airflow and relief from sinus pressure. Pseudoephedrine (found in Sudafed) is a powerful option available behind the pharmacy counter, while phenylephrine (found in some OTC products) offers a milder effect.

Pharmacist Tip: Keep both on hand if possible — ibuprofen is anti-inflammatory, while acetaminophen is often gentler on the stomach. Make sure to read the label carefully and never double-dose, especially with combination products.

Why This Matters in the USA:

With dry indoor heating and varying climates, sinus infections can follow untreated colds. Decongestants help you breathe better and reduce secondary infections.

• Avoid using nasal sprays for more than 3 days in a row to prevent rebound congestion.
• Always follow label instructions, especially if you have high blood pressure or heart conditions.

Cough Suppressant and Expectorant Combo

Saline sprays are a simple, drug-free way to ease nasal congestion, flush out allergens, and keep your nasal passages moist — especially in dry winter months. Unlike medicated sprays, saline can be used multiple times a day without side effects. For more serious congestion or sinus irritation, a neti pot or squeeze bottle saline rinse (like NeilMed Sinus Rinse) can be a game-changer. These are especially helpful for people living in arid or heavily polluted areas in the U.S., or for allergy sufferers.